2qnp
From Proteopedia
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[[Image:2qnp.png|left|200px]] | [[Image:2qnp.png|left|200px]] | ||
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{{STRUCTURE_2qnp| PDB=2qnp | SCENE= }} | {{STRUCTURE_2qnp| PDB=2qnp | SCENE= }} | ||
===HIV-1 Protease in complex with a iodo decorated pyrrolidine-based inhibitor=== | ===HIV-1 Protease in complex with a iodo decorated pyrrolidine-based inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[2qnp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QNP OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018348517</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Capsid maturation]] | [[Category: Capsid maturation]] | ||
[[Category: Core protein]] | [[Category: Core protein]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Dna integration]] | [[Category: Dna integration]] | ||
[[Category: Dna recombination]] | [[Category: Dna recombination]] | ||
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[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
- | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:43:32 2009'' |
Revision as of 21:01, 7 January 2013
HIV-1 Protease in complex with a iodo decorated pyrrolidine-based inhibitor
Template:ABSTRACT PUBMED 18348517
About this Structure
2qnp is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s
Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Blum, A. | Boettcher, J. | Diederich, W E. | Heine, A. | Klebe, G. | Aid | Aspartyl protease | Capsid maturation | Core protein | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hydrolase | Lipoprotein | Magnesium | Membrane | Metal-binding | Multifunctional enzyme | Myristate | Nuclease | Nucleotidyltransferase | Phosphorylation | Protease | Protein-ligand complex | Rna-binding | Rna-directed dna polymerase | Transferase | Viral nucleoprotein | Virion | Zinc-finger