3wrp
From Proteopedia
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{{STRUCTURE_3wrp| PDB=3wrp | SCENE= }} | {{STRUCTURE_3wrp| PDB=3wrp | SCENE= }} | ||
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===FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR=== | ===FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR=== | ||
+ | {{ABSTRACT_PUBMED_3375234}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | |
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==About this Structure== | ==About this Structure== | ||
- | + | [[3wrp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WRP OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:003375234</ref><references group="xtra"/><references/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Sigler, P B.]] | [[Category: Sigler, P B.]] | ||
[[Category: Zhang, R G.]] | [[Category: Zhang, R G.]] | ||
[[Category: Dna binding regulatory protein]] | [[Category: Dna binding regulatory protein]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:51:16 2009'' |
Revision as of 08:09, 16 May 2013
Contents |
FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
Template:ABSTRACT PUBMED 3375234
Function
[TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
About this Structure
3wrp is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Lawson CL, Zhang RG, Schevitz RW, Otwinowski Z, Joachimiak A, Sigler PB. Flexibility of the DNA-binding domains of trp repressor. Proteins. 1988;3(1):18-31. PMID:3375234 doi:http://dx.doi.org/10.1002/prot.340030103