Template:STRUCTURE 1hsg

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hsg]], resolution 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hsg]], [[Resolution|resolution]] 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+Mk1+B+902'>AC1</scene>
|LIGAND= <scene name='pdbligand=MK1:N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY+BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE'>MK1</scene>
|LIGAND= <scene name='pdbligand=MK1:N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY+BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE'>MK1</scene>
|GENE= HIV-1 PROTEASE FROM THE NY5 ISOLATE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
|GENE= HIV-1 PROTEASE FROM THE NY5 ISOLATE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00077 RVP]</span>
 
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsg OCA], [http://www.ebi.ac.uk/pdbsum/1hsg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hsg RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsg OCA], [http://www.ebi.ac.uk/pdbsum/1hsg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hsg RCSB]</span>
|FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0016779 | text = nucleotidyltransferase activity}}{{GO|id=GO:0004523 | text = ribonuclease H activity}}{{GO|id=GO:0003676 | text = nucleic acid binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004519 | text = endonuclease activity}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0003964 | text = RNA-directed DNA polymerase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005198 | text = structural molecule activity}}{{GO|id=GO:0003723 | text = RNA binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0003887 | text = DNA-directed DNA polymerase activity}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0004518 | text = nuclease activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0008907 | text = integrase activity}}
|FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0016779 | text = nucleotidyltransferase activity}}{{GO|id=GO:0004523 | text = ribonuclease H activity}}{{GO|id=GO:0003676 | text = nucleic acid binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004519 | text = endonuclease activity}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0003964 | text = RNA-directed DNA polymerase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005198 | text = structural molecule activity}}{{GO|id=GO:0003723 | text = RNA binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0003887 | text = DNA-directed DNA polymerase activity}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0004518 | text = nuclease activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0008907 | text = integrase activity}}
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|COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0019013 | text = viral nucleocapsid}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0019028 | text = viral capsid}}{{GO|id=GO:0019012 | text = virion}}
|COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0019013 | text = viral nucleocapsid}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0019028 | text = viral capsid}}{{GO|id=GO:0019012 | text = virion}}
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgA00 1Hsga00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgB00 1Hsgb00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010659 Ipr010659], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010999 Ipr010999], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001995 Ipr001995], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008916 Ipr008916], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010661 Ipr010661], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002156 Ipr002156], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001878 Ipr001878], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000071 Ipr000071], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000721 Ipr000721], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012337 Ipr012337], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001037 Ipr001037], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008919 Ipr008919], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003308 Ipr003308], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000477 Ipr000477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013084 Ipr013084], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001584 Ipr001584]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00077 PF00077]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=26541 d1hsga_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=26542 d1hsgb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03367 P03367]</span>
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgA00 1Hsga00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgB00 1Hsgb00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010659 Ipr010659], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010999 Ipr010999], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001995 Ipr001995], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008916 Ipr008916], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010661 Ipr010661], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002156 Ipr002156], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001878 Ipr001878], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000071 Ipr000071], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000721 Ipr000721], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012337 Ipr012337], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001037 Ipr001037], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008919 Ipr008919], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003308 Ipr003308], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000477 Ipr000477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013084 Ipr013084], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001584 Ipr001584]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00077 PF00077]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=26541 d1hsga_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=26542 d1hsgb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03367 P03367]</span>
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|CONSURF={{!}}-
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|uPDB=1HSG|CONSURF={{!}}-
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Revision as of 06:33, 21 January 2010

Drag the structure with the mouse to rotate
1hsg, resolution 2.00Å ()
Sites:
Ligands:
Gene: HIV-1 PROTEASE FROM THE NY5 ISOLATE (Human immunodeficiency virus 1)
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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