2aze
From Proteopedia
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[[Image:2aze.png|left|200px]] | [[Image:2aze.png|left|200px]] | ||
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{{STRUCTURE_2aze| PDB=2aze | SCENE= }} | {{STRUCTURE_2aze| PDB=2aze | SCENE= }} | ||
===Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer=== | ===Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer=== | ||
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{{ABSTRACT_PUBMED_16360038}} | {{ABSTRACT_PUBMED_16360038}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Pinealoma with bilateral retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2aze]] is a 3 chain structure of [[Retinoblastoma protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZE OCA]. | |
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| + | ==See Also== | ||
| + | *[[Retinoblastoma protein|Retinoblastoma protein]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016360038</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Gall, A L.]] | [[Category: Gall, A L.]] | ||
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[[Category: Zheng, N.]] | [[Category: Zheng, N.]] | ||
[[Category: Beta sandwich]] | [[Category: Beta sandwich]] | ||
| - | [[Category: | + | [[Category: Cell cycle]] |
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Revision as of 18:13, 26 July 2012
Contents |
Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Template:ABSTRACT PUBMED 16360038
About this Structure
2aze is a 3 chain structure of Retinoblastoma protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rubin SM, Gall AL, Zheng N, Pavletich NP. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell. 2005 Dec 16;123(6):1093-106. PMID:16360038 doi:10.1016/j.cell.2005.09.044
