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2hd6

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==About this Structure==
==About this Structure==
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2HD6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD6 OCA].
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[[2hd6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD6 OCA].
==Reference==
==Reference==
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[[Category: Simone, G De.]]
[[Category: Simone, G De.]]
[[Category: Vitale, R M.]]
[[Category: Vitale, R M.]]
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[[Category: Lyase]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:53:43 2009''
 

Revision as of 22:32, 14 March 2011

Template:STRUCTURE 2hd6

Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.

Template:ABSTRACT PUBMED 16942027

About this Structure

2hd6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT. Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX. J Med Chem. 2006 Sep 7;49(18):5544-51. PMID:16942027 doi:http://dx.doi.org/10.1021/jm060531j
  • Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406

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