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1t7i
From Proteopedia
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===The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.=== | ===The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1t7i]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7I OCA]. | |
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| + | ==See Also== | ||
| + | *[[Virus protease|Virus protease]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015771427</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Drug resitance]] | [[Category: Drug resitance]] | ||
[[Category: Hiv-1 protease]] | [[Category: Hiv-1 protease]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Substrate envelope]] | [[Category: Substrate envelope]] | ||
[[Category: Thermodynamic]] | [[Category: Thermodynamic]] | ||
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Revision as of 19:34, 26 July 2012
Contents |
The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.
Template:ABSTRACT PUBMED 15771427
About this Structure
1t7i is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p
