1ra5

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[[Image:1ra5.png|left|200px]]
[[Image:1ra5.png|left|200px]]
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{{STRUCTURE_1ra5| PDB=1ra5 | SCENE= }}
{{STRUCTURE_1ra5| PDB=1ra5 | SCENE= }}
===Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.===
===Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.===
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{{ABSTRACT_PUBMED_15381761}}
{{ABSTRACT_PUBMED_15381761}}
==About this Structure==
==About this Structure==
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1RA5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA5 OCA].
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[[1ra5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA5 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:15381761</ref><references group="xtra"/>
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<ref group="xtra">PMID:015381761</ref><references group="xtra"/>
[[Category: Cytosine deaminase]]
[[Category: Cytosine deaminase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: D314a mutant]]
[[Category: D314a mutant]]
[[Category: Hexamer]]
[[Category: Hexamer]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:18:28 2009''
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Revision as of 10:19, 4 January 2013

Template:STRUCTURE 1ra5

Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.

Template:ABSTRACT PUBMED 15381761

About this Structure

1ra5 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Mahan SD, Ireton GC, Knoeber C, Stoddard BL, Black ME. Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng Des Sel. 2004 Aug;17(8):625-33. Epub 2004 Sep 20. PMID:15381761 doi:10.1093/protein/gzh074

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