2qzk

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[[Image:2qzk.png|left|200px]]
[[Image:2qzk.png|left|200px]]
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{{STRUCTURE_2qzk| PDB=2qzk | SCENE= }}
{{STRUCTURE_2qzk| PDB=2qzk | SCENE= }}
===Crystal structure of human Beta Secretase complexed with I21===
===Crystal structure of human Beta Secretase complexed with I21===
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{{ABSTRACT_PUBMED_17827011}}
{{ABSTRACT_PUBMED_17827011}}
==About this Structure==
==About this Structure==
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2QZK is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZK OCA].
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[[2qzk]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZK OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17827011</ref><references group="xtra"/>
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<ref group="xtra">PMID:017827011</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Munshi, S.]]
[[Category: Munshi, S.]]
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[[Category: Alternative splicing]]
 
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace]]
[[Category: Bace]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:31:04 2009''
 

Revision as of 19:57, 26 July 2012

Image:2qzk.png

Template:STRUCTURE 2qzk

Contents

Crystal structure of human Beta Secretase complexed with I21

Template:ABSTRACT PUBMED 17827011

About this Structure

2qzk is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Moore KP, Zhu H, Rajapakse HA, McGaughey GB, Colussi D, Price EA, Sankaranarayanan S, Simon AJ, Pudvah NT, Hochman JH, Allison T, Munshi SK, Graham SL, Vacca JP, Nantermet PG. Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5831-5. Epub 2007 Aug 23. PMID:17827011 doi:10.1016/j.bmcl.2007.08.040

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