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1t7j

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==About this Structure==
==About this Structure==
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1T7J is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7J OCA].
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1T7J is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7J OCA].
==Reference==
==Reference==
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[[Category: Drug resitance]]
[[Category: Drug resitance]]
[[Category: Hiv-1 protease]]
[[Category: Hiv-1 protease]]
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[[Category: Hydrolase]]
[[Category: Substrate envelope]]
[[Category: Substrate envelope]]
[[Category: Thermodynamic]]
[[Category: Thermodynamic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:58:56 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:51:15 2010''

Revision as of 05:44, 21 July 2010

Template:STRUCTURE 1t7j

crystal structure of inhibitor amprenavir in complex with a multi-drug resistant variant of HIV-1 protease (L63P/V82T/I84V)

Template:ABSTRACT PUBMED 15771427

About this Structure

1T7J is a 2 chains structure with sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p

Page seeded by OCA on Wed Jul 21 09:51:15 2010

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