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1rqc
From Proteopedia
(Difference between revisions)
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[[Image:1rqc.png|left|200px]] | [[Image:1rqc.png|left|200px]] | ||
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{{STRUCTURE_1rqc| PDB=1rqc | SCENE= }} | {{STRUCTURE_1rqc| PDB=1rqc | SCENE= }} | ||
===Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design=== | ===Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design=== | ||
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{{ABSTRACT_PUBMED_15010544}} | {{ABSTRACT_PUBMED_15010544}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1rqc]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RQC OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015010544</ref><ref group="xtra">PMID:016516468</ref><references group="xtra"/> |
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
[[Category: Hirsh, I.]] | [[Category: Hirsh, I.]] | ||
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[[Category: Turley, S.]] | [[Category: Turley, S.]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:02:18 2009'' | ||
Revision as of 10:35, 4 January 2013
Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design
Template:ABSTRACT PUBMED 15010544
About this Structure
1rqc is a 10 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
Reference
- Robien MA, Nguyen KT, Kumar A, Hirsh I, Turley S, Pei D, Hol WG. An improved crystal form of Plasmodium falciparum peptide deformylase. Protein Sci. 2004 Apr;13(4):1155-63. Epub 2004 Mar 9. PMID:15010544 doi:http://dx.doi.org/10.1110/ps.03456404
- Joshi AA, Viswanathan CL. Docking studies and development of novel 5-heteroarylamino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as potential antimalarials. Bioorg Med Chem Lett. 2006 May 15;16(10):2613-7. Epub 2006 Mar 3. PMID:16516468 doi:10.1016/j.bmcl.2006.02.038
