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2h4y

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{{Seed}}
 
[[Image:2h4y.png|left|200px]]
[[Image:2h4y.png|left|200px]]
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==About this Structure==
==About this Structure==
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2H4Y is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H4Y OCA].
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[[2h4y]] is a 3 chain structure of [[Caspase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H4Y OCA].
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==See Also==
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*[[Caspase|Caspase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18590738</ref><references group="xtra"/>
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<ref group="xtra">PMID:018590738</ref><references group="xtra"/>
[[Category: Caspase-1]]
[[Category: Caspase-1]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Wells, J A.]]
[[Category: Wells, J A.]]
[[Category: Allosteric site]]
[[Category: Allosteric site]]
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[[Category: Caspase-1]]
 
[[Category: Dimer interface]]
[[Category: Dimer interface]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:04:52 2009''
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Revision as of 05:08, 30 May 2012

Template:STRUCTURE 2h4y

Contents

Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)

Template:ABSTRACT PUBMED 18590738

About this Structure

2h4y is a 3 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Datta D, Scheer JM, Romanowski MJ, Wells JA. An allosteric circuit in caspase-1. J Mol Biol. 2008 Sep 19;381(5):1157-67. Epub 2008 Jun 20. PMID:18590738 doi:10.1016/j.jmb.2008.06.040

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