1pzl
From Proteopedia
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{{STRUCTURE_1pzl| PDB=1pzl | SCENE= }} | {{STRUCTURE_1pzl| PDB=1pzl | SCENE= }} | ||
===Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide=== | ===Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide=== | ||
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{{ABSTRACT_PUBMED_14982928}} | {{ABSTRACT_PUBMED_14982928}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: MODY, type I OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600281 600281]], Diabetes mellitus, noninsulin-dependent OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600281 600281]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1pzl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZL OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014982928</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chi, Y I.]] | [[Category: Chi, Y I.]] | ||
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[[Category: Shoelson, S.]] | [[Category: Shoelson, S.]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:32:50 2009'' | ||
Revision as of 10:11, 2 January 2013
Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide
Template:ABSTRACT PUBMED 14982928
About this Structure
1pzl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Duda K, Chi YI, Shoelson SE. Structural basis for HNF-4alpha activation by ligand and coactivator binding. J Biol Chem. 2004 May 28;279(22):23311-6. Epub 2004 Feb 24. PMID:14982928 doi:10.1074/jbc.M400864200
