2gkl
From Proteopedia
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[[Image:2gkl.png|left|200px]] | [[Image:2gkl.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[2gkl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GKL OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Lactamase]] | [[Category: Lactamase]] | ||
[[Category: Zn]] | [[Category: Zn]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:40:45 2009'' |
Revision as of 20:40, 14 March 2011
Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate
Template:ABSTRACT PUBMED 17307979
About this Structure
2gkl is a 1 chain structure with sequence from Aeromonas hydrophila. Full crystallographic information is available from OCA.
Reference
- Horsfall LE, Garau G, Lienard BM, Dideberg O, Schofield CJ, Frere JM, Galleni M. Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila. Antimicrob Agents Chemother. 2007 Jun;51(6):2136-42. Epub 2007 Feb 16. PMID:17307979 doi:10.1128/AAC.00866-06
- Garau G, Bebrone C, Anne C, Galleni M, Frere JM, Dideberg O. A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. J Mol Biol. 2005 Jan 28;345(4):785-95. PMID:15588826 doi:http://dx.doi.org/10.1016/j.jmb.2004.10.070
- Garau G, Garcia-Saez I, Bebrone C, Anne C, Mercuri P, Galleni M, Frere JM, Dideberg O. Update of the standard numbering scheme for class B beta-lactamases. Antimicrob Agents Chemother. 2004 Jul;48(7):2347-9. PMID:15215079 doi:http://dx.doi.org/10.1128/AAC.48.7.2347-2349.2004
- Carfi A, Pares S, Duee E, Galleni M, Duez C, Frere JM, Dideberg O. The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J. 1995 Oct 16;14(20):4914-21. PMID:7588620