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1y98

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{{Seed}}
 
[[Image:1y98.png|left|200px]]
[[Image:1y98.png|left|200px]]
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{{STRUCTURE_1y98| PDB=1y98 | SCENE= }}
{{STRUCTURE_1y98| PDB=1y98 | SCENE= }}
===Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.===
===Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.===
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{{ABSTRACT_PUBMED_16101277}}
{{ABSTRACT_PUBMED_16101277}}
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==Disease==
 
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Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]]
 
==About this Structure==
==About this Structure==
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1Y98 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y98 OCA].
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[[1y98]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y98 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16101277</ref><references group="xtra"/>
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<ref group="xtra">PMID:016101277</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Birrane, G.]]
[[Category: Birrane, G.]]
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[[Category: Ladias, J A.A.]]
[[Category: Ladias, J A.A.]]
[[Category: Varma, A K.]]
[[Category: Varma, A K.]]
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[[Category: Antitumor protein]]
[[Category: Brca1]]
[[Category: Brca1]]
[[Category: Brct]]
[[Category: Brct]]
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[[Category: Ctip]]
[[Category: Ctip]]
[[Category: Phosphopeptide]]
[[Category: Phosphopeptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:02:38 2009''
 

Revision as of 17:14, 5 January 2013

Template:STRUCTURE 1y98

Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.

Template:ABSTRACT PUBMED 16101277

About this Structure

1y98 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Varma AK, Brown RS, Birrane G, Ladias JA. Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. Biochemistry. 2005 Aug 23;44(33):10941-6. PMID:16101277 doi:10.1021/bi0509651

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