1i5r
From Proteopedia
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[[Image:1i5r.png|left|200px]] | [[Image:1i5r.png|left|200px]] | ||
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{{STRUCTURE_1i5r| PDB=1i5r | SCENE= }} | {{STRUCTURE_1i5r| PDB=1i5r | SCENE= }} | ||
===TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX=== | ===TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX=== | ||
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{{ABSTRACT_PUBMED_12223444}} | {{ABSTRACT_PUBMED_12223444}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1i5r]] is a 1 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I5R OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012223444</ref><ref group="xtra">PMID:018533708</ref><references group="xtra"/> |
[[Category: Estradiol 17-beta-dehydrogenase]] | [[Category: Estradiol 17-beta-dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Hybrid]] | [[Category: Hybrid]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 22:31, 26 July 2012
Contents |
TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX
Template:ABSTRACT PUBMED 12223444
About this Structure
1i5r is a 1 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity. FASEB J. 2002 Nov;16(13):1829-31. Epub 2002 Sep 5. PMID:12223444 doi:10.1096/fj.02-0026fje
- Schuster D, Nashev LG, Kirchmair J, Laggner C, Wolber G, Langer T, Odermatt A. Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. J Med Chem. 2008 Jul 24;51(14):4188-99. Epub 2008 Jun 6. PMID:18533708 doi:10.1021/jm800054h
