1c89
From Proteopedia
(New page: 200px<br /> <applet load="1c89" size="450" color="white" frame="true" align="right" spinBox="true" caption="1c89" /> '''NMR STRUCTURE OF INTRAMOLECULAR DIMER ANTIF...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1C89 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pachycara_brachycephalum Pachycara brachycephalum]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1C89 OCA]]. | + | 1C89 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pachycara_brachycephalum Pachycara brachycephalum]]. Structure known Active Sites: IC1 and IC2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1C89 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: thermal hysteresis protein]] | [[Category: thermal hysteresis protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:21:59 2007'' |
Revision as of 12:17, 30 October 2007
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NMR STRUCTURE OF INTRAMOLECULAR DIMER ANTIFREEZE PROTEIN RD3, 40 SA STRUCTURES
Overview
The structure of a new antifreeze protein (AFP) variant, RD3, from, antarctic eel pout (Rhigophila dearborni) with enhanced activity has been, determined for the first time by nuclear magnetic resonance spectroscopy., RD3 comprises a unique translational topology of two homologous type III, AFP globular domains, each containing one flat, ice binding plane. The ice, binding plane of the N domain is located approximately 3.5 A "behind" that, of the C domain. The two ice binding planes are located laterally with an, angle of 32 +/- 12 degrees between the planes. These results suggest that, the C domain plane of RD3 binds first to the ice [1010] prism plane in the, <0001> direction, which induces successive ice binding of the N domain in, the <0101> direction. This manner of ice ... [(full description)]
About this Structure
1C89 is a [Single protein] structure of sequence from [Pachycara brachycephalum]. Structure known Active Sites: IC1 and IC2. Full crystallographic information is available from [OCA].
Reference
NMR analysis of type III antifreeze protein intramolecular dimer. Structural basis for enhanced activity., Miura K, Ohgiya S, Hoshino T, Nemoto N, Suetake T, Miura A, Spyracopoulos L, Kondo H, Tsuda S, J Biol Chem. 2001 Jan 12;276(2):1304-10. PMID:11010977
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