2an3

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{{Seed}}
 
[[Image:2an3.png|left|200px]]
[[Image:2an3.png|left|200px]]
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{{ABSTRACT_PUBMED_16363801}}
{{ABSTRACT_PUBMED_16363801}}
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==Disease==
 
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Known disease associated with this structure: Hypertension, essential, 145500 (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171190 171190]]
 
==About this Structure==
==About this Structure==
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2AN3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA].
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[[2an3]] is a 2 chain structure of [[Phenylethanolamine N-methyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA].
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==See Also==
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*[[Phenylethanolamine N-methyltransferase]]
==Reference==
==Reference==
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[[Category: S-adenosyl-l-methionine]]
[[Category: S-adenosyl-l-methionine]]
[[Category: Substrate structure]]
[[Category: Substrate structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:00:50 2009''
 

Revision as of 23:25, 26 December 2010

Template:STRUCTURE 2an3

Contents

Structure of PNMT with S-adenosyl-L-homocysteine and the semi-rigid analogue acceptor substrate cis-(1R,2S)-2-amino-1-tetralol.

Template:ABSTRACT PUBMED 16363801

About this Structure

2an3 is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:16363801 doi:http://dx.doi.org/10.1021/bi051636b

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