This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2an3
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2an3.png|left|200px]] | [[Image:2an3.png|left|200px]] | ||
| Line 18: | Line 17: | ||
--> | --> | ||
{{ABSTRACT_PUBMED_16363801}} | {{ABSTRACT_PUBMED_16363801}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Hypertension, essential, 145500 (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171190 171190]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2an3]] is a 2 chain structure of [[Phenylethanolamine N-methyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Phenylethanolamine N-methyltransferase]] | ||
==Reference== | ==Reference== | ||
| Line 39: | Line 38: | ||
[[Category: S-adenosyl-l-methionine]] | [[Category: S-adenosyl-l-methionine]] | ||
[[Category: Substrate structure]] | [[Category: Substrate structure]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:00:50 2009'' | ||
Revision as of 23:25, 26 December 2010
Contents |
Structure of PNMT with S-adenosyl-L-homocysteine and the semi-rigid analogue acceptor substrate cis-(1R,2S)-2-amino-1-tetralol.
Template:ABSTRACT PUBMED 16363801
About this Structure
2an3 is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:16363801 doi:http://dx.doi.org/10.1021/bi051636b
