1xs7
From Proteopedia
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===Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase).=== | ===Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase).=== | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[1xs7]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XS7 OCA]. | |
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+ | ==See Also== | ||
+ | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015582402</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Bace]] | [[Category: Bace]] | ||
[[Category: Beta secretase]] | [[Category: Beta secretase]] | ||
- | [[Category: Crystallography]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
+ | [[Category: Hydrolase]] | ||
[[Category: Memapsin2]] | [[Category: Memapsin2]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:10:00 2009'' |
Revision as of 23:53, 26 July 2012
Contents |
Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase).
Template:ABSTRACT PUBMED 15582402
About this Structure
1xs7 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ghosh AK, Devasamudram T, Hong L, DeZutter C, Xu X, Weerasena V, Koelsch G, Bilcer G, Tang J. Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase). Bioorg Med Chem Lett. 2005 Jan 3;15(1):15-20. PMID:15582402 doi:10.1016/j.bmcl.2004.10.084
Categories: Homo sapiens | Memapsin 2 | Bilcer, G. | DeZutter, C. | Devasamudram, T. | Ghosh, A. | Hong, L. | Koelsch, G. | Tang, J. | Weerasena, V. | Xu, X. | Acid protease | Alzheimer's disease | Asp2 | Aspartic protease | Bace | Beta secretase | Drug design | Hydrolase | Memapsin2