2qq7
From Proteopedia
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{{STRUCTURE_2qq7| PDB=2qq7 | SCENE= }} | {{STRUCTURE_2qq7| PDB=2qq7 | SCENE= }} | ||
===Crystal structure of drug resistant SRC kinase domain with irreversible inhibitor=== | ===Crystal structure of drug resistant SRC kinase domain with irreversible inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2qq7]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQ7 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018316192</ref><references group="xtra"/> |
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Rauh, D.]] | [[Category: Rauh, D.]] | ||
[[Category: Rode, H B.]] | [[Category: Rode, H B.]] | ||
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[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Drug resistance]] | [[Category: Drug resistance]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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Revision as of 23:55, 26 July 2012
Contents |
Crystal structure of drug resistant SRC kinase domain with irreversible inhibitor
Template:ABSTRACT PUBMED 18316192
About this Structure
2qq7 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Michalczyk A, Kluter S, Rode HB, Simard JR, Grutter C, Rabiller M, Rauh D. Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg Med Chem. 2008 Apr 1;16(7):3482-8. Epub 2008 Feb 20. PMID:18316192 doi:10.1016/j.bmc.2008.02.053
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Gruetter, C. | Michalczyk, A. | Rauh, D. | Rode, H B. | Atp-binding | Drug resistance | Irreversible inhibitor | Lipoprotein | Myristate | Nucleotide-binding | Phosphorylation | Proto-oncogene | Sh2 domain | Sh3 domain | Src kinase domain | Transferase | Tyrosine-protein kinase
