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2k05

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[[Image:2k05.png|left|200px]]
[[Image:2k05.png|left|200px]]
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{{STRUCTURE_2k05| PDB=2k05 | SCENE= }}
{{STRUCTURE_2k05| PDB=2k05 | SCENE= }}
===Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21===
===Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21===
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{{ABSTRACT_PUBMED_18799424}}
{{ABSTRACT_PUBMED_18799424}}
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==Disease==
 
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Known disease associated with this structure: Myelokathexis, isolated OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=162643 162643]], WHIM syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=162643 162643]]
 
==About this Structure==
==About this Structure==
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2K05 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K05 OCA].
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[[2k05]] is a 4 chain structure of [[CXC chemokine receptor type 4]] and [[Stromal Derived Factor 1]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K05 OCA].
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==See Also==
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*[[CXC chemokine receptor type 4|CXC chemokine receptor type 4]]
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*[[Stromal Derived Factor 1|Stromal Derived Factor 1]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18799424</ref><references group="xtra"/>
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<ref group="xtra">PMID:018799424</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peterson, F C.]]
[[Category: Peterson, F C.]]
[[Category: Veldkamp, C T.]]
[[Category: Veldkamp, C T.]]
[[Category: Volkman, B F.]]
[[Category: Volkman, B F.]]
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[[Category: Alternative splicing]]
 
[[Category: Chemokine]]
[[Category: Chemokine]]
[[Category: Chemotaxis]]
[[Category: Chemotaxis]]
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[[Category: Transducer]]
[[Category: Transducer]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:34:33 2009''
 

Revision as of 00:30, 27 July 2012

Image:2k05.png

Template:STRUCTURE 2k05

Contents

Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21

Template:ABSTRACT PUBMED 18799424

About this Structure

2k05 is a 4 chain structure of CXC chemokine receptor type 4 and Stromal Derived Factor 1 with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  • Veldkamp CT, Seibert C, Peterson FC, De la Cruz NB, Haugner JC 3rd, Basnet H, Sakmar TP, Volkman BF. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci Signal. 2008 Sep 16;1(37):ra4. PMID:18799424 doi:1/37/ra4

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