3bgl
From Proteopedia
(Difference between revisions)
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| - | {{Seed}} | ||
[[Image:3bgl.png|left|200px]] | [[Image:3bgl.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_18155906}} | {{ABSTRACT_PUBMED_18155906}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Statins, attenuated cholesterol lowering by OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142910 142910]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3bgl]] is a 4 chain structure of [[HMG-CoA Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGL OCA]. | |
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| + | ==See Also== | ||
| + | *[[HMG-CoA Reductase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Steroid biosynthesis]] | [[Category: Steroid biosynthesis]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:46:10 2009'' | ||
Revision as of 01:03, 27 December 2010
Contents |
Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors
Template:ABSTRACT PUBMED 18155906
About this Structure
3bgl is a 4 chain structure of HMG-CoA Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Park WK, Kennedy RM, Larsen SD, Miller S, Roth BD, Song Y, Steinbaugh BA, Sun K, Tait BD, Kowala MC, Trivedi BK, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu GH, Robertson A, Sekerke C. Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1151-6. Epub 2007 Dec 5. PMID:18155906 doi:10.1016/j.bmcl.2007.11.124
