2nxr
From Proteopedia
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[[Image:2nxr.png|left|200px]] | [[Image:2nxr.png|left|200px]] | ||
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{{STRUCTURE_2nxr| PDB=2nxr | SCENE= }} | {{STRUCTURE_2nxr| PDB=2nxr | SCENE= }} | ||
===Structural effects of hydrophobic mutations on the active site of human carbonic anhydrase II=== | ===Structural effects of hydrophobic mutations on the active site of human carbonic anhydrase II=== | ||
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{{ABSTRACT_PUBMED_17330962}} | {{ABSTRACT_PUBMED_17330962}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2nxr]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXR OCA]. | |
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| + | ==See Also== | ||
| + | *[[Carbonic anhydrase|Carbonic anhydrase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017330962</ref><references group="xtra"/> |
[[Category: Carbonate dehydratase]] | [[Category: Carbonate dehydratase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Carbonic anhydrase]] | [[Category: Carbonic anhydrase]] | ||
[[Category: Histidine 64]] | [[Category: Histidine 64]] | ||
| + | [[Category: Lyase]] | ||
[[Category: Proton transfer]] | [[Category: Proton transfer]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:12:00 2009'' | ||
Revision as of 01:26, 27 July 2012
Contents |
Structural effects of hydrophobic mutations on the active site of human carbonic anhydrase II
Template:ABSTRACT PUBMED 17330962
About this Structure
2nxr is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Fisher SZ, Tu C, Bhatt D, Govindasamy L, Agbandje-McKenna M, McKenna R, Silverman DN. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II. Biochemistry. 2007 Mar 27;46(12):3803-13. Epub 2007 Mar 2. PMID:17330962 doi:10.1021/bi602620k
