2c5o
From Proteopedia
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===DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN=== | ===DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2c5o]] is a 4 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5O OCA]. | |
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| + | ==See Also== | ||
| + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | ||
| + | *[[Cyclin|Cyclin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016492568</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Fischer, P M.]] | [[Category: Fischer, P M.]] | ||
[[Category: Gibson, D.]] | [[Category: Gibson, D.]] | ||
| - | [[Category: Imcnae]] | ||
[[Category: Kontopidis, G.]] | [[Category: Kontopidis, G.]] | ||
[[Category: Mcinnes, C.]] | [[Category: Mcinnes, C.]] | ||
| + | [[Category: Mcnae, I.]] | ||
[[Category: Mezna, M.]] | [[Category: Mezna, M.]] | ||
[[Category: Pandalaneni, S R.]] | [[Category: Pandalaneni, S R.]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine/threonine-protein]] | [[Category: Serine/threonine-protein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:28:43 2009'' | ||
Revision as of 01:48, 27 July 2012
Contents |
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
Template:ABSTRACT PUBMED 16492568
About this Structure
2c5o is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:http://dx.doi.org/10.1016/j.chembiol.2005.11.011
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Fischer, P M. | Gibson, D. | Kontopidis, G. | Mcinnes, C. | Mcnae, I. | Mezna, M. | Pandalaneni, S R. | Thomas, M. | Walkinshaw, M D. | Wang, S. | Wood, G. | Atp-binding | Cdk2 | Cell cycle | Cell division | Cyclin | Differential inhibition | Kinase | Mitosis | Nucleotide-binding | Phosphorylation | Serine/threonine-protein | Transferase
