This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2f81
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2f81.png|left|200px]] | [[Image:2f81.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2f81", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2f81| PDB=2f81 | SCENE= }} | {{STRUCTURE_2f81| PDB=2f81 | SCENE= }} | ||
===HIV-1 Protease mutant L90M complexed with inhibitor TMC114=== | ===HIV-1 Protease mutant L90M complexed with inhibitor TMC114=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16480273}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16480273 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16480273}} | {{ABSTRACT_PUBMED_16480273}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2f81]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F81 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016480273</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| Line 29: | Line 17: | ||
[[Category: Weber, I T.]] | [[Category: Weber, I T.]] | ||
[[Category: Hiv-1 protease-inhibitor complex]] | [[Category: Hiv-1 protease-inhibitor complex]] | ||
| - | + | [[Category: Hydrolase]] | |
| - | + | ||
Revision as of 14:36, 7 January 2013
HIV-1 Protease mutant L90M complexed with inhibitor TMC114
Template:ABSTRACT PUBMED 16480273
About this Structure
2f81 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Kovalevsky AY, Tie Y, Liu F, Boross PI, Wang YF, Leshchenko S, Ghosh AK, Harrison RW, Weber IT. Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M. J Med Chem. 2006 Feb 23;49(4):1379-87. PMID:16480273 doi:http://dx.doi.org/10.1021/jm050943c
