2o22

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{{ABSTRACT_PUBMED_17256834}}
{{ABSTRACT_PUBMED_17256834}}
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==Disease==
 
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Known disease associated with this structure: Leukemia/lymphoma, B-cell OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151430 151430]]
 
==About this Structure==
==About this Structure==
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2O22 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O22 OCA].
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2O22 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O22 OCA].
==Reference==
==Reference==
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[[Category: Bcl]]
[[Category: Bcl]]
[[Category: Complex]]
[[Category: Complex]]
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[[Category: Nmr]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:55:02 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:05:40 2010''

Revision as of 05:53, 22 December 2010

Image:2o22.png

Template:STRUCTURE 2o22

Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand

Template:ABSTRACT PUBMED 17256834

About this Structure

2O22 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Bruncko M, Oost TK, Belli BA, Ding H, Joseph MK, Kunzer A, Martineau D, McClellan WJ, Mitten M, Ng SC, Nimmer PM, Oltersdorf T, Park CM, Petros AM, Shoemaker AR, Song X, Wang X, Wendt MD, Zhang H, Fesik SW, Rosenberg SH, Elmore SW. Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL. J Med Chem. 2007 Feb 22;50(4):641-62. Epub 2007 Jan 26. PMID:17256834 doi:http://dx.doi.org/10.1021/jm061152t

Page seeded by OCA on Wed Dec 22 09:05:40 2010

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