2rgp
From Proteopedia
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{{STRUCTURE_2rgp| PDB=2rgp | SCENE= }} | {{STRUCTURE_2rgp| PDB=2rgp | SCENE= }} | ||
===Structure of EGFR in complex with hydrazone, a potent dual inhibitor=== | ===Structure of EGFR in complex with hydrazone, a potent dual inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2rgp]] is a 1 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGP OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018653333</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Abad, M C.]] | [[Category: Abad, M C.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Anti-oncogene]] | [[Category: Anti-oncogene]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | [[Category: Ubl conjugation]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:03:42 2009'' | ||
Revision as of 02:35, 27 July 2012
Contents |
Structure of EGFR in complex with hydrazone, a potent dual inhibitor
Template:ABSTRACT PUBMED 18653333
About this Structure
2rgp is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA. 4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:18653333 doi:10.1016/j.bmcl.2008.07.020
