2gfs
From Proteopedia
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[[Image:2gfs.png|left|200px]] | [[Image:2gfs.png|left|200px]] | ||
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{{STRUCTURE_2gfs| PDB=2gfs | SCENE= }} | {{STRUCTURE_2gfs| PDB=2gfs | SCENE= }} | ||
===P38 Kinase Crystal Structure in complex with RO3201195=== | ===P38 Kinase Crystal Structure in complex with RO3201195=== | ||
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{{ABSTRACT_PUBMED_16509574}} | {{ABSTRACT_PUBMED_16509574}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2gfs]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GFS OCA]. | |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016509574</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: P38]] | [[Category: P38]] | ||
[[Category: Serine/threonine kinase]] | [[Category: Serine/threonine kinase]] | ||
| - | + | [[Category: Signaling protein]] | |
| - | + | [[Category: Transferase]] | |
Revision as of 03:41, 27 July 2012
Contents |
P38 Kinase Crystal Structure in complex with RO3201195
Template:ABSTRACT PUBMED 16509574
About this Structure
2gfs is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Goldstein DM, Alfredson T, Bertrand J, Browner MF, Clifford K, Dalrymple SA, Dunn J, Freire-Moar J, Harris S, Labadie SS, La Fargue J, Lapierre JM, Larrabee S, Li F, Papp E, McWeeney D, Ramesha C, Roberts R, Rotstein D, San Pablo B, Sjogren EB, So OY, Talamas FX, Tao W, Trejo A, Villasenor A, Welch M, Welch T, Weller P, Whiteley PE, Young K, Zipfel S. Discovery of S-[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)ph enyl]methanone (RO3201195), an orally bioavailable and highly selective inhibitor of p38 MAP kinase. J Med Chem. 2006 Mar 9;49(5):1562-75. PMID:16509574 doi:10.1021/jm050736c
