1n5o
From Proteopedia
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[[Image:1n5o.png|left|200px]] | [[Image:1n5o.png|left|200px]] | ||
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{{STRUCTURE_1n5o| PDB=1n5o | SCENE= }} | {{STRUCTURE_1n5o| PDB=1n5o | SCENE= }} | ||
===Structural consequences of a cancer-causing BRCA1-BRCT missense mutation=== | ===Structural consequences of a cancer-causing BRCA1-BRCT missense mutation=== | ||
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{{ABSTRACT_PUBMED_12427738}} | {{ABSTRACT_PUBMED_12427738}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1n5o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5O OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012427738</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Glover, J N.M.]] | [[Category: Glover, J N.M.]] | ||
[[Category: Williams, R S.]] | [[Category: Williams, R S.]] | ||
| + | [[Category: Antitumor protein]] | ||
[[Category: Brca1]] | [[Category: Brca1]] | ||
[[Category: Brct]] | [[Category: Brct]] | ||
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[[Category: Missense mutation]] | [[Category: Missense mutation]] | ||
[[Category: Protein folding]] | [[Category: Protein folding]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:06:44 2009'' | ||
Revision as of 20:11, 5 December 2012
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
Template:ABSTRACT PUBMED 12427738
About this Structure
1n5o is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Williams RS, Glover JN. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J Biol Chem. 2003 Jan 24;278(4):2630-5. Epub 2002 Nov 8. PMID:12427738 doi:10.1074/jbc.M210019200
