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3tgf
From Proteopedia
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{{STRUCTURE_3tgf| PDB=3tgf | SCENE= }} | {{STRUCTURE_3tgf| PDB=3tgf | SCENE= }} | ||
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===THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA=== | ===THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA=== | ||
| + | {{ABSTRACT_PUBMED_2050136}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/TGFA_HUMAN TGFA_HUMAN]] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3tgf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGF OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:002050136</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Campbell, I D.]] | [[Category: Campbell, I D.]] | ||
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[[Category: Wilkinson, A J.]] | [[Category: Wilkinson, A J.]] | ||
[[Category: Growth factor]] | [[Category: Growth factor]] | ||
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Revision as of 07:58, 16 May 2013
Contents |
THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA
Template:ABSTRACT PUBMED 2050136
Function
[TGFA_HUMAN] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
About this Structure
3tgf is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Harvey TS, Wilkinson AJ, Tappin MJ, Cooke RM, Campbell ID. The solution structure of human transforming growth factor alpha. Eur J Biochem. 1991 Jun 15;198(3):555-62. PMID:2050136
