2r3w
From Proteopedia
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{{STRUCTURE_2r3w| PDB=2r3w | SCENE= }} | {{STRUCTURE_2r3w| PDB=2r3w | SCENE= }} | ||
===I84V HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor=== | ===I84V HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2r3w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3W OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018692068</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
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Revision as of 21:24, 7 January 2013
I84V HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor
Template:ABSTRACT PUBMED 18692068
About this Structure
2r3w is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062
