3bu3
From Proteopedia
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{{STRUCTURE_3bu3| PDB=3bu3 | SCENE= }} | {{STRUCTURE_3bu3| PDB=3bu3 | SCENE= }} | ||
===Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide=== | ===Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide=== | ||
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{{ABSTRACT_PUBMED_18278056}} | {{ABSTRACT_PUBMED_18278056}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3bu3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BU3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Insulin receptor|Insulin receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018278056</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Hubbard, S R.]] | [[Category: Hubbard, S R.]] | ||
[[Category: Wu, J.]] | [[Category: Wu, J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Carbohydrate metabolism]] | [[Category: Carbohydrate metabolism]] | ||
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[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Peptide]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Substrate]] | [[Category: Substrate]] | ||
[[Category: Transducer]] | [[Category: Transducer]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:45:08 2009'' | ||
Revision as of 21:36, 7 January 2013
Contents |
Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide
Template:ABSTRACT PUBMED 18278056
About this Structure
3bu3 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wu J, Tseng YD, Xu CF, Neubert TA, White MF, Hubbard SR. Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat Struct Mol Biol. 2008 Mar;15(3):251-8. Epub 2008 Feb 17. PMID:18278056 doi:10.1038/nsmb.1388
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Hubbard, S R. | Wu, J. | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Insulin receptor | Irk | Irs2 | Kinase | Krlb | Membrane | Nucleotide-binding | Phosphoprotein | Substrate | Transducer | Transferase | Transmembrane | Tyrosine-protein kinase
