2zm3
From Proteopedia
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===Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor=== | ===Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Insulin-like growth factor I, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147370 147370]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2zm3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Insulin-like growth factor receptor|Insulin-like growth factor receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018501599</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
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[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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Revision as of 19:50, 20 October 2012
Contents |
Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
Template:ABSTRACT PUBMED 18501599
About this Structure
2zm3 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W. Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599 doi:10.1016/j.bmcl.2008.04.044
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Boschelli, F. | Dwyer, B. | Johnson, M. | Mayer, S C. | Xu, W. | Atp-binding | Cleavage on pair of basic residue | Disease mutation | Glycoprotein | Igfr | Membrane | Nucleotide-binding | Phosphoprotein | Protein-inhibitor complex | Receptor | Transferase | Transmembrane | Tyrosine kinase | Tyrosine-protein kinase
