2ftd

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===Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound===
===Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound===
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{{ABSTRACT_PUBMED_16509577}}
==About this Structure==
==About this Structure==
2FTD is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTD OCA].
2FTD is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTD OCA].
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==Reference==
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<ref group="xtra">PMID:16509577</ref><references group="xtra"/>
[[Category: Cathepsin K]]
[[Category: Cathepsin K]]
[[Category: Macaca mulatta]]
[[Category: Macaca mulatta]]
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[[Category: Sulfhydryl proteinase]]
[[Category: Sulfhydryl proteinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 29 20:36:29 2009''

Revision as of 17:36, 29 April 2009

Template:STRUCTURE 2ftd

Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound

Template:ABSTRACT PUBMED 16509577

About this Structure

2FTD is a 2 chains structure of sequences from Macaca mulatta. Full crystallographic information is available from OCA.

Reference

  • Yamashita DS, Marquis RW, Xie R, Nidamarthy SD, Oh HJ, Jeong JU, Erhard KF, Ward KW, Roethke TJ, Smith BR, Cheng HY, Geng X, Lin F, Offen PH, Wang B, Nevins N, Head MS, Haltiwanger RC, Narducci Sarjeant AA, Liable-Sands LM, Zhao B, Smith WW, Janson CA, Gao E, Tomaszek T, McQueney M, James IE, Gress CJ, Zembryki DL, Lark MW, Veber DF. Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors. J Med Chem. 2006 Mar 9;49(5):1597-612. PMID:16509577 doi:10.1021/jm050915u

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