2qy0
From Proteopedia
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[[Image:2qy0.png|left|200px]] | [[Image:2qy0.png|left|200px]] | ||
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{{STRUCTURE_2qy0| PDB=2qy0 | SCENE= }} | {{STRUCTURE_2qy0| PDB=2qy0 | SCENE= }} | ||
===Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts=== | ===Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts=== | ||
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{{ABSTRACT_PUBMED_17996945}} | {{ABSTRACT_PUBMED_17996945}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: C1r/C1s deficiency, combined OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=216950 216950]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2qy0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QY0 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017996945</ref><references group="xtra"/> |
[[Category: Complement subcomponent C1r]] | [[Category: Complement subcomponent C1r]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Innate immunity]] | [[Category: Innate immunity]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Sushi]] | [[Category: Sushi]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:34:44 2009'' | ||
Revision as of 22:39, 7 January 2013
Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts
Template:ABSTRACT PUBMED 17996945
About this Structure
2qy0 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kardos J, Harmat V, Pallo A, Barabas O, Szilagyi K, Graf L, Naray-Szabo G, Goto Y, Zavodszky P, Gal P. Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r. Mol Immunol. 2008 Mar;45(6):1752-60. Epub 2007 Nov 9. PMID:17996945 doi:10.1016/j.molimm.2007.09.031
Categories: Complement subcomponent C1r | Homo sapiens | Barabas, O. | Gal, P. | Goto, Y. | Graf, L. | Harmat, V. | Kardos, J. | Naray-Szabo, G. | Pallo, A. | Szilagyi, K. | Zavodszky, P. | Beta barrel | Complement | Complement pathway | Egf-like domain | Glycoprotein | Hydrolase | Hydroxylation | Immune response | Innate immunity | Phosphorylation | Serine protease | Sushi
