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2dqt
From Proteopedia
(Difference between revisions)
| Line 35: | Line 35: | ||
[[Category: Esterolytic]] | [[Category: Esterolytic]] | ||
[[Category: Fab]] | [[Category: Fab]] | ||
| + | [[Category: Immune system]] | ||
[[Category: Immunoglobulin]] | [[Category: Immunoglobulin]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 19 08:38:39 2009'' |
Revision as of 05:38, 19 April 2009
High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog
Template:ABSTRACT PUBMED 17428500
About this Structure
2DQT is a 2 chains structure of sequences from Mus musculus. This structure supersedes the now removed PDB entry 1hyx. Full crystallographic information is available from OCA.
Reference
- Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I. Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis. J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:17428500 doi:10.1016/j.jmb.2007.03.023
- Miyashita H, Hara T, Tanimura R, Fukuyama S, Cagnon C, Kohara A, Fujii I. Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization. J Mol Biol. 1997 Apr 18;267(5):1247-57. PMID:9150409 doi:10.1006/jmbi.1997.0938
- Miyashita H, Hara T, Tamimura R, Tanaka F, Kikuchi M, Fujii I. A common ancestry for multiple catalytic antibodies generated against a single transition-state analog. Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10757. PMID:7938025
- Miyashita H, Hara T, Tanimura R, Tanaka F, Kikuchi M, Fujii I. A common ancestry for multiple catalytic antibodies generated against a single transition-state analog. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6045-9. PMID:8016113
- Miyashita H, Karaki Y, Kikuchi M, Fujii I. Prodrug activation via catalytic antibodies. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5337-40. PMID:8506382
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