1o5m
From Proteopedia
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{{STRUCTURE_1o5m| PDB=1o5m | SCENE= }} | {{STRUCTURE_1o5m| PDB=1o5m | SCENE= }} | ||
===Structure of FPT bound to the inhibitor SCH66336=== | ===Structure of FPT bound to the inhibitor SCH66336=== | ||
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{{ABSTRACT_PUBMED_10377218}} | {{ABSTRACT_PUBMED_10377218}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1o5m]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5M OCA]. | |
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| + | ==See Also== | ||
| + | *[[Farnesyltransferase|Farnesyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010377218</ref><references group="xtra"/> |
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Ganguly, A K.]] | [[Category: Ganguly, A K.]] | ||
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[[Category: Weber, P C.]] | [[Category: Weber, P C.]] | ||
[[Category: Protein inhibitor complex]] | [[Category: Protein inhibitor complex]] | ||
| - | + | [[Category: Transferase-transferase inhibitor complex]] | |
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Revision as of 10:23, 27 July 2012
Contents |
Structure of FPT bound to the inhibitor SCH66336
Template:ABSTRACT PUBMED 10377218
About this Structure
1o5m is a 2 chain structure of Farnesyltransferase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Strickland CL, Weber PC, Windsor WT, Wu Z, Le HV, Albanese MM, Alvarez CS, Cesarz D, del Rosario J, Deskus J, Mallams AK, Njoroge FG, Piwinski JJ, Remiszewski S, Rossman RR, Taveras AG, Vibulbhan B, Doll RJ, Girijavallabhan VM, Ganguly AK. Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships. J Med Chem. 1999 Jun 17;42(12):2125-35. PMID:10377218 doi:http://dx.doi.org/10.1021/jm990030g
