1xkk
From Proteopedia
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[[Image:1xkk.png|left|200px]] | [[Image:1xkk.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1xkk]] is a 1 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The June 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Epidermal Growth Factor Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_6 10.2210/rcsb_pdb/mom_2010_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKK OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:15374980</ref><references group="xtra"/> | <ref group="xtra">PMID:15374980</ref><references group="xtra"/> | ||
| + | [[Category: Epidermal Growth Factor Receptor]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Alligood, K J.]] | [[Category: Alligood, K J.]] | ||
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[[Category: Epidermal growth factor receptor]] | [[Category: Epidermal growth factor receptor]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 09:34, 26 December 2010
Contents |
EGFR kinase domain complexed with a quinazoline inhibitor- GW572016
Template:ABSTRACT PUBMED 15374980
About this Structure
1xkk is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH, Ellis B, Pennisi C, Horne E, Lackey K, Alligood KJ, Rusnak DW, Gilmer TM, Shewchuk L. A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res. 2004 Sep 15;64(18):6652-9. PMID:15374980 doi:10.1158/0008-5472.CAN-04-1168
Categories: Epidermal Growth Factor Receptor | Homo sapiens | RCSB PDB Molecule of the Month | Transferase | Alligood, K J. | Dickerson, S H. | Ellis, B. | Gilmer, T M. | Hassell, A. | Horne, E. | Lackey, K. | McDonald, O B. | Pennisi, C. | Rusnak, D W. | Shewchuk, L M. | Truesdale, A T. | Wood, E R. | Yuan, D. | Egfr | Epidermal growth factor receptor | Kinase
