This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2i0h
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2i0h.png|left|200px]] | [[Image:2i0h.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2i0h", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2i0h| PDB=2i0h | SCENE= }} | {{STRUCTURE_2i0h| PDB=2i0h | SCENE= }} | ||
===The structure of p38alpha in complex with an arylpyridazinone=== | ===The structure of p38alpha in complex with an arylpyridazinone=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16945533}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16945533 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16945533}} | {{ABSTRACT_PUBMED_16945533}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2i0h]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0H OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016945533</ref><ref group="xtra">PMID:017070898</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
| Line 37: | Line 28: | ||
[[Category: Inhibitor design]] | [[Category: Inhibitor design]] | ||
[[Category: Serine/threonine kinase]] | [[Category: Serine/threonine kinase]] | ||
| - | + | [[Category: Transferase]] | |
| - | + | ||
Revision as of 11:19, 27 July 2012
Contents |
The structure of p38alpha in complex with an arylpyridazinone
Template:ABSTRACT PUBMED 16945533
About this Structure
2i0h is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Natarajan SR, Heller ST, Nam K, Singh SB, Scapin G, Patel S, Thompson JE, Fitzgerald CE, O'Keefe SJ. p38 MAP kinase inhibitors. Part 6: 2-arylpyridazin-3-ones as templates for inhibitor design. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5809-13. Epub 2006 Aug 30. PMID:16945533 doi:10.1016/j.bmcl.2006.08.074
- Lahiri SD, Zhang G, Dunaway-Mariano D, Allen KN. Diversification of function in the haloacid dehalogenase enzyme superfamily: The role of the cap domain in hydrolytic phosphoruscarbon bond cleavage. Bioorg Chem. 2006 Dec;34(6):394-409. Epub 2006 Oct 27. PMID:17070898 doi:10.1016/j.bioorg.2006.09.007
