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3drp

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==About this Structure==
==About this Structure==
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3DRP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRP OCA].
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[[3drp]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRP OCA].
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==See Also==
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*[[Reverse transcriptase]]
==Reference==
==Reference==
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[[Category: Nucleotidyltrasferase]]
[[Category: Nucleotidyltrasferase]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:16:41 2009''
 

Revision as of 20:34, 26 December 2010

Template:STRUCTURE 3drp

Contents

HIV reverse transcriptase in complex with inhibitor R8e

Template:ABSTRACT PUBMED 18826204

About this Structure

3drp is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Reid JC, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses. J Med Chem. 2008 Oct 1. PMID:18826204 doi:10.1021/jm800856c

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