1py5
From Proteopedia
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[[Image:1py5.png|left|200px]] | [[Image:1py5.png|left|200px]] | ||
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{{STRUCTURE_1py5| PDB=1py5 | SCENE= }} | {{STRUCTURE_1py5| PDB=1py5 | SCENE= }} | ||
===Crystal Structure of TGF-beta receptor I kinase with inhibitor=== | ===Crystal Structure of TGF-beta receptor I kinase with inhibitor=== | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_15177479}}, adds the Publication Abstract to the page | ||
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{{ABSTRACT_PUBMED_15177479}} | {{ABSTRACT_PUBMED_15177479}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1py5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY5 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015177479</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Receptor i]] | [[Category: Receptor i]] | ||
[[Category: Tgf-beta]] | [[Category: Tgf-beta]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 09:50, 2 January 2013
Crystal Structure of TGF-beta receptor I kinase with inhibitor
Template:ABSTRACT PUBMED 15177479
About this Structure
1py5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sawyer JS, Beight DW, Britt KS, Anderson BD, Campbell RM, Goodson T Jr, Herron DK, Li HY, McMillen WT, Mort N, Parsons S, Smith EC, Wagner JR, Yan L, Zhang F, Yingling JM. Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3581-4. PMID:15177479 doi:http://dx.doi.org/10.1016/j.bmcl.2004.04.007
