1s9g

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==About this Structure==
==About this Structure==
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1S9G is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9G OCA].
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1S9G is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9G OCA].
==Reference==
==Reference==
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[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
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[[Category: Clark, A D.]]
[[Category: Das, K.]]
[[Category: Das, K.]]
[[Category: Decorte, B.]]
[[Category: Decorte, B.]]
[[Category: Hughes, S H.]]
[[Category: Hughes, S H.]]
[[Category: Janssen, P A.]]
[[Category: Janssen, P A.]]
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[[Category: Jr., A D.Clark.]]
 
[[Category: Kukla, M J.]]
[[Category: Kukla, M J.]]
[[Category: Lewi, P J.]]
[[Category: Lewi, P J.]]
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[[Category: Reverse transcriptase]]
[[Category: Reverse transcriptase]]
[[Category: Rt]]
[[Category: Rt]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:37:06 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:14:38 2010''

Revision as of 07:04, 13 October 2010

Template:STRUCTURE 1s9g

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R120394.

Template:ABSTRACT PUBMED 15115397

About this Structure

1S9G is a 2 chains structure with sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Das K, Clark AD Jr, Lewi PJ, Heeres J, De Jonge MR, Koymans LM, Vinkers HM, Daeyaert F, Ludovici DW, Kukla MJ, De Corte B, Kavash RW, Ho CY, Ye H, Lichtenstein MA, Andries K, Pauwels R, De Bethune MP, Boyer PL, Clark P, Hughes SH, Janssen PA, Arnold E. Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants. J Med Chem. 2004 May 6;47(10):2550-60. PMID:15115397 doi:http://dx.doi.org/10.1021/jm030558s

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