2fir
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2fir.png|left|200px]] | [[Image:2fir.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2fir", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2fir| PDB=2fir | SCENE= }} | {{STRUCTURE_2fir| PDB=2fir | SCENE= }} | ||
===Crystal structure of DFPR-VIIa/sTF=== | ===Crystal structure of DFPR-VIIa/sTF=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16757484}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16757484 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16757484}} | {{ABSTRACT_PUBMED_16757484}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2fir]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIR OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Factor VIIa|Factor VIIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016757484</ref><references group="xtra"/> |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 35: | Line 23: | ||
[[Category: Schmidt, A E.]] | [[Category: Schmidt, A E.]] | ||
[[Category: Schreuder, H.]] | [[Category: Schreuder, H.]] | ||
| + | [[Category: Blood clotting]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Factor viia]] | [[Category: Factor viia]] | ||
| - | [[Category: | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Oxyanion hole]] | [[Category: Oxyanion hole]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
| - | [[Category: Sodium]] | ||
[[Category: Soluble tissue factor]] | [[Category: Soluble tissue factor]] | ||
| - | [[Category: Zinc]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:43:37 2009'' | ||
Revision as of 13:15, 27 July 2012
| |||||||||
| 2fir, resolution 2.00Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , , | ||||||||
| Non-Standard Residues: | |||||||||
| Gene: | F7 (Homo sapiens), F3 (Homo sapiens) | ||||||||
| Activity: | Coagulation factor VIIa, with EC number 3.4.21.21 | ||||||||
| Related: | 1dan, 2a2q, 2aer, 2b8o | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Crystal structure of DFPR-VIIa/sTF
Template:ABSTRACT PUBMED 16757484
About this Structure
2fir is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200
