3bwm
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3bwm| PDB=3bwm | SCENE= }} | {{STRUCTURE_3bwm| PDB=3bwm | SCENE= }} | ||
===Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC=== | ===Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC=== | ||
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{{ABSTRACT_PUBMED_18486144}} | {{ABSTRACT_PUBMED_18486144}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Panic disorder, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=116790 116790]], Schizophrenia, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=116790 116790]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3bwm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWM OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018486144</ref><references group="xtra"/> |
[[Category: Catechol O-methyltransferase]] | [[Category: Catechol O-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Catecholamine metabolism]] | [[Category: Catecholamine metabolism]] | ||
[[Category: Comt]] | [[Category: Comt]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Dnc]] | [[Category: Dnc]] | ||
[[Category: Magnesium]] | [[Category: Magnesium]] | ||
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[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
[[Category: Neurotransmitter degradation]] | [[Category: Neurotransmitter degradation]] | ||
- | [[Category: Polymorphism]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
[[Category: S-adenosyl-l-methionine]] | [[Category: S-adenosyl-l-methionine]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:10:43 2009'' |
Revision as of 20:46, 7 January 2013
Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC
Template:ABSTRACT PUBMED 18486144
About this Structure
3bwm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rutherford K, Le Trong I, Stenkamp RE, Parson WW. Crystal structures of human 108V and 108M catechol O-methyltransferase. J Mol Biol. 2008 Jun 27;380(1):120-30. Epub 2008 Apr 23. PMID:18486144 doi:10.1016/j.jmb.2008.04.040
Categories: Catechol O-methyltransferase | Homo sapiens | Parson, W W. | Rutherford, K. | Stenkamp, R E. | Trong, I Le. | Alternative initiation | Catecholamine metabolism | Comt | Dnc | Magnesium | Membrane | Methyltransferase | Neurotransmitter degradation | Rossmann fold | S-adenosyl-l-methionine | Sam | Transferase | Transmembrane