1un5

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{{Seed}}
 
[[Image:1un5.png|left|200px]]
[[Image:1un5.png|left|200px]]
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==About this Structure==
==About this Structure==
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1UN5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UN5 OCA].
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[[1un5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UN5 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:14756559</ref><references group="xtra"/>
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<ref group="xtra">PMID:14756559</ref><ref group="xtra">PMID:9918722</ref><ref group="xtra">PMID:1698454</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Pancreatic ribonuclease]]
[[Category: Pancreatic ribonuclease]]
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[[Category: Homolog scanning mutagenesis]]
[[Category: Homolog scanning mutagenesis]]
[[Category: Hybrid]]
[[Category: Hybrid]]
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[[Category: Hydrolase]]
[[Category: Pancreatic ribonuclease]]
[[Category: Pancreatic ribonuclease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:17:03 2009''
 

Revision as of 18:30, 14 March 2011

Template:STRUCTURE 1un5

ARH-II, AN ANGIOGENIN/RNASE A CHIMERA

Template:ABSTRACT PUBMED 14756559

About this Structure

1un5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Holloway DE, Chavali GB, Hares MC, Baker MD, Subbarao GV, Shapiro R, Acharya KR. Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Biochemistry. 2004 Feb 10;43(5):1230-41. PMID:14756559 doi:10.1021/bi035654+
  • Leonidas DD, Shapiro R, Allen SC, Subbarao GV, Veluraja K, Acharya KR. Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J Mol Biol. 1999 Jan 22;285(3):1209-33. PMID:9918722 doi:10.1006/jmbi.1998.2378
  • Harper JW, Fox EA, Shapiro R, Vallee BL. Mutagenesis of residues flanking Lys-40 enhances the enzymatic activity and reduces the angiogenic potency of angiogenin. Biochemistry. 1990 Aug 7;29(31):7297-302. PMID:1698454

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