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2ipj
From Proteopedia
(Difference between revisions)
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[[Category: Hydroxysteroid dehydrogenase]] | [[Category: Hydroxysteroid dehydrogenase]] | ||
[[Category: Open conformation]] | [[Category: Open conformation]] | ||
| + | [[Category: Oxidoreductase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 10:34:49 2009'' |
Revision as of 07:34, 13 May 2009
Contents |
Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant Y24A in complex with NADP+ and epi-testosterone
Template:ABSTRACT PUBMED 17442338
Disease
Known disease associated with this structure: Obesity, hyperphagia, and developmental delay OMIM:[600450]
About this Structure
2IPJ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Faucher F, Cantin L, Pereira de Jesus-Tran K, Lemieux M, Luu-The V, Labrie F, Breton R. Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding. J Mol Biol. 2007 Jun 1;369(2):525-40. Epub 2007 Mar 27. PMID:17442338 doi:10.1016/j.jmb.2007.03.058
Page seeded by OCA on Wed May 13 10:34:49 2009
