1t4f
From Proteopedia
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{{STRUCTURE_1t4f| PDB=1t4f | SCENE= }} | {{STRUCTURE_1t4f| PDB=1t4f | SCENE= }} | ||
===Structure of human MDM2 in complex with an optimized p53 peptide=== | ===Structure of human MDM2 in complex with an optimized p53 peptide=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1t4f]] is a 2 chain structure of [[MDM2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4F OCA]. | |
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| + | ==See Also== | ||
| + | *[[MDM2|MDM2]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015715460</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Carver, T E.]] | [[Category: Carver, T E.]] | ||
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[[Category: Schubert, C.]] | [[Category: Schubert, C.]] | ||
[[Category: Zhao, S Y.]] | [[Category: Zhao, S Y.]] | ||
| + | [[Category: Ligase]] | ||
[[Category: Mdm2-p53 peptide complex]] | [[Category: Mdm2-p53 peptide complex]] | ||
[[Category: P53-binding protein mdm2 oncoprotein mdm2 double minute 2 protein hdm2]] | [[Category: P53-binding protein mdm2 oncoprotein mdm2 double minute 2 protein hdm2]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:49:25 2009'' | ||
Revision as of 14:07, 27 July 2012
Contents |
Structure of human MDM2 in complex with an optimized p53 peptide
Template:ABSTRACT PUBMED 15715460
About this Structure
1t4f is a 2 chain structure of MDM2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF. Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells. J Med Chem. 2005 Feb 24;48(4):909-12. PMID:15715460 doi:10.1021/jm049137g
