2f9b
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2f9b.png|left|200px]] | [[Image:2f9b.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2f9b", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2f9b| PDB=2f9b | SCENE= }} | {{STRUCTURE_2f9b| PDB=2f9b | SCENE= }} | ||
===Discovery of Novel Heterocyclic Factor VIIa Inhibitors=== | ===Discovery of Novel Heterocyclic Factor VIIa Inhibitors=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16460932}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16460932 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16460932}} | {{ABSTRACT_PUBMED_16460932}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2f9b]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9B OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Factor VIIa|Factor VIIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016460932</ref><references group="xtra"/> |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 43: | Line 31: | ||
[[Category: Yu, C.]] | [[Category: Yu, C.]] | ||
[[Category: Active site-directed inhibitor]] | [[Category: Active site-directed inhibitor]] | ||
| + | [[Category: Hydrolase-blood clotting complex]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Short hydrogen bond]] | [[Category: Short hydrogen bond]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:53:56 2009'' | ||
Revision as of 14:14, 27 July 2012
Contents |
Discovery of Novel Heterocyclic Factor VIIa Inhibitors
Template:ABSTRACT PUBMED 16460932
About this Structure
2f9b is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rai R, Kolesnikov A, Sprengeler PA, Torkelson S, Ton T, Katz BA, Yu C, Hendrix J, Shrader WD, Stephens R, Cabuslay R, Sanford E, Young WB. Discovery of novel heterocyclic factor VIIa inhibitors. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2270-3. Epub 2006 Feb 3. PMID:16460932 doi:10.1016/j.bmcl.2006.01.017
Categories: Coagulation factor VIIa | Homo sapiens | Cabuslay, R. | Hendrix, J. | Katz, B A. | Kolesnikov, A. | Rai, R. | Sanford, E. | Shrader, W D. | Sprengeler, P A. | Stephens, R. | Ton, T. | Torkelson, S. | Young, W B. | Yu, C. | Active site-directed inhibitor | Hydrolase-blood clotting complex | Serine protease | Short hydrogen bond
