3g1m

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(New page: '''Unreleased structure''' The entry 3g1m is ON HOLD Authors: Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Pou...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3g1m.jpg|left|200px]]
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The entry 3g1m is ON HOLD
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{{STRUCTURE_3g1m| PDB=3g1m | SCENE= }}
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Authors: Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
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===EthR from Mycobacterium tuberculosis in complex with compound BDM31381===
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Description: EthR from Mycobacterium tuberculosis in complex with compound BDM31381
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:54:14 2009''
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{{ABSTRACT_PUBMED_19412174}}
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==About this Structure==
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3G1M is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1M OCA].
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==Reference==
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<ref group="xtra">PMID:19412174</ref><ref group="xtra">PMID:16243584</ref><ref group="xtra">PMID:15494316</ref><ref group="xtra">PMID:14651620</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Aumercier, M.]]
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[[Category: Baulard, A R.]]
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[[Category: Bifani, P.]]
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[[Category: Carette, X.]]
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[[Category: Delcroix, G.]]
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[[Category: Deprez, B.]]
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[[Category: Deprez-Poulain, R.]]
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[[Category: Desroses, M.]]
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[[Category: Dirie, B.]]
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[[Category: Frenois, F.]]
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[[Category: Leroux, F.]]
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[[Category: Locht, C.]]
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[[Category: Mathys, V.]]
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[[Category: Singhal, A.]]
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[[Category: Villeret, V.]]
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[[Category: Willand, N.]]
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[[Category: Willery, E.]]
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[[Category: Dna-binding]]
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[[Category: Tetr family]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:36:10 2009''

Revision as of 17:36, 22 July 2009

Image:3g1m.jpg

Template:STRUCTURE 3g1m

EthR from Mycobacterium tuberculosis in complex with compound BDM31381

Template:ABSTRACT PUBMED 19412174

About this Structure

3G1M is a 1 chain structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Willand N, Dirie B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Deprez-Poulain R, Delcroix G, Frenois F, Aumercier M, Locht C, Villeret V, Deprez B, Baulard AR. Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat Med. 2009 May;15(5):537-44. Epub 2009 May 3. PMID:19412174 doi:10.1038/nm.1950
  • Frenois F, Baulard AR, Villeret V. Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis. Tuberculosis (Edinb). 2006 Mar;86(2):110-4. Epub 2005 Oct 21. PMID:16243584 doi:10.1016/j.tube.2005.07.005
  • Frenois F, Engohang-Ndong J, Locht C, Baulard AR, Villeret V. Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis. Mol Cell. 2004 Oct 22;16(2):301-7. PMID:15494316 doi:10.1016/j.molcel.2004.09.020
  • Engohang-Ndong J, Baillat D, Aumercier M, Bellefontaine F, Besra GS, Locht C, Baulard AR. EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator. Mol Microbiol. 2004 Jan;51(1):175-88. PMID:14651620

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