3en7

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[[Image:3en7.png|left|200px]]
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{{STRUCTURE_3en7| PDB=3en7 | SCENE= }}
{{STRUCTURE_3en7| PDB=3en7 | SCENE= }}
===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor===
===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor===
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{{ABSTRACT_PUBMED_18849971}}
{{ABSTRACT_PUBMED_18849971}}
==About this Structure==
==About this Structure==
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3EN7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EN7 OCA].
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[[3en7]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EN7 OCA].
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==See Also==
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*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18849971</ref><references group="xtra"/>
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<ref group="xtra">PMID:018849971</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Knight, Z A.]]
[[Category: Knight, Z A.]]
[[Category: Shokat, K M.]]
[[Category: Shokat, K M.]]
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[[Category: Alternative splicing]]
 
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
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[[Category: Tyrosine]]
[[Category: Tyrosine]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:08:58 2009''
 

Revision as of 15:22, 27 July 2012

Template:STRUCTURE 3en7

Contents

Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor

Template:ABSTRACT PUBMED 18849971

About this Structure

3en7 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  • Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117

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