3en7
From Proteopedia
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===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor=== | ===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[3en7]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EN7 OCA]. | |
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+ | ==See Also== | ||
+ | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018849971</ref><references group="xtra"/> |
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Knight, Z A.]] | [[Category: Knight, Z A.]] | ||
[[Category: Shokat, K M.]] | [[Category: Shokat, K M.]] | ||
- | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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[[Category: Tyrosine]] | [[Category: Tyrosine]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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Revision as of 15:22, 27 July 2012
Contents |
Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor
Template:ABSTRACT PUBMED 18849971
About this Structure
3en7 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Apsel, B. | Blair, J A. | Knight, Z A. | Shokat, K M. | Atp-binding | Inhibitor | Kinase | Kinase-inhibitor complex | Lipoprotein | Multitarget | Myristate | Nucleotide-binding | Phosphoinositide | Phosphoprotein | Polypharmacology | Proto-oncogene | Pyrazolopyrimidine | Sh2 domain | Sh3 domain | Signaling | Src | Transferase | Tyrosine | Tyrosine-protein kinase