1uk4

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{{STRUCTURE_1uk4| PDB=1uk4 | SCENE= }}
{{STRUCTURE_1uk4| PDB=1uk4 | SCENE= }}
===Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor===
===Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor===
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{{ABSTRACT_PUBMED_14585926}}
{{ABSTRACT_PUBMED_14585926}}
==About this Structure==
==About this Structure==
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1UK4 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UK4 OCA].
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[[1uk4]] is a 5 chain structure of [[SARS Coronavirus Main Proteinase]] with sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UK4 OCA].
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==See Also==
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*[[SARS Coronavirus Main Proteinase|SARS Coronavirus Main Proteinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:14585926</ref><references group="xtra"/>
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<ref group="xtra">PMID:014585926</ref><ref group="xtra">PMID:015690493</ref><ref group="xtra">PMID:016638531</ref><references group="xtra"/>
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[[Category: Human sars coronavirus]]
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[[Category: Sars coronavirus]]
[[Category: Anand, K.]]
[[Category: Anand, K.]]
[[Category: Bartlam, M.]]
[[Category: Bartlam, M.]]
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[[Category: Anti-parallel a-helice]]
[[Category: Anti-parallel a-helice]]
[[Category: Anti-parallel b-barrel]]
[[Category: Anti-parallel b-barrel]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:33:53 2009''
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Revision as of 15:53, 27 July 2012

Image:1uk4.png

Template:STRUCTURE 1uk4

Contents

Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor

Template:ABSTRACT PUBMED 14585926

About this Structure

1uk4 is a 5 chain structure of SARS Coronavirus Main Proteinase with sequence from Sars coronavirus. Full crystallographic information is available from OCA.

See Also

Reference

  • Yang H, Yang M, Ding Y, Liu Y, Lou Z, Zhou Z, Sun L, Mo L, Ye S, Pang H, Gao GF, Anand K, Bartlam M, Hilgenfeld R, Rao Z. The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13190-5. Epub 2003 Oct 29. PMID:14585926 doi:10.1073/pnas.1835675100
  • Pang YP. Three-dimensional model of a substrate-bound SARS chymotrypsin-like cysteine proteinase predicted by multiple molecular dynamics simulations: catalytic efficiency regulated by substrate binding. Proteins. 2004 Dec 1;57(4):747-57. PMID:15690493 doi:10.1002/prot.20249
  • Wu CY, King KY, Kuo CJ, Fang JM, Wu YT, Ho MY, Liao CL, Shie JJ, Liang PH, Wong CH. Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease. Chem Biol. 2006 Mar;13(3):261-8. PMID:16638531 doi:10.1016/j.chembiol.2005.12.008

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